FreeSurfer may be run on Windows via the VirtualBox applicaion. VirtualBox is supplied by Sun Microsystem. You should first install that on your Windows system, downloaded from here: http://www.virtualbox.org/wiki/Downloads Choose the 'x86' download for Windows. To extract the .rar file, you might need to get the 7-zip utility from: http://www.7-zip.org Once the files are extracted, then use the VirtualBox Wizard to select the .vdi file as the 'hard disk image'. Select as much memory as you can dedicate to the image (2GB or more). Upon successful installation, the VirtualBox should open an Ubuntu instance, automatically login, display a terminal with freesurfer properly setup. The root password, should you need it, is 'brain2009'. You should be able to run apps such as: tksurfer bert rh inflated -annotation aparc You may need to disable 3D graphics accelleration in the VirtualBox video configuration for tksurfer to work properly (on some systems, acceleration works, others, not). You will also need to create this link as root in order for qdec and freeview to work: cd /usr/lib ln -s libtiff.so.4 libtiff.so.3 It is possible to configure the VirtualBox to allow access to a USB hard disk (which might store your subject data). To enable access, in the VirtualBox main window, click on the yellow 'gear' icon, then click on the USB option. Under 'Device Filters', click 'Add Empty', do this once for each USB port your likely to use with your virtual machine, then click OK. This will allow the USB pass-through of a device connected to the PC to reach the Ubuntu environment. Be sure to install the VirtualBoxUSB driver if prompted to do so. A correctly attached USB drive will appear under the /media folder in Ubuntu. To debug attachments, you can 'tail -f /var/log/messages' and look for USB related messages. Thanks to Pedro Paulo Oliveira for creating this VirtualBox. NJS