Cortical Hubs
The 'Cortical Hubs' (CHubs) are regions-of-interest defined by cortical thickness differences between older controls and individuals classified as having AD, created using the OASIS data set. These ROIS were used in the study The Dynamics of Cortical and Hippocampal Atrophy in Alzheimer Disease, Sabuncu et al.. See also: Supplemental
Freesurfer v5.2 (and v5.1 local) contains these ROIs as labels, found in the directory $FREESURFER_HOME/subjects/fsaverage/label. There are eight:
FS label name |
name used in paper |
?h.oasis.chubs.ifc |
inferior frontal cortex |
?h.oasis.chubs.ipc |
inferior parietal cortex |
?h.oasis.chubs.ips |
inferior parietal sulcus |
?h.oasis.chubs.lateraltemporal |
lateral temporal cortex |
?h.oasis.chubs.medialpfc |
not used in paper |
?h.oasis.chubs.mtl |
medial temporal lobe (eg. entorhinal cortex) |
?h.oasis.chubs.retrosplenial |
posterior cingulate |
?h.oasis.chubs.tp |
temporalpolar cortex |