These are answers to the 'Study Questions'

What is the input for FreeSurfer?

A T1-weighted (MPRAGE) image, 1 mm isotropic

What is a volume and a surface?

A volume is a 3D data set that typically contains either intensity information from the original MRI or the results of segmenting the data into tissue classes. A surface is a reconstructed boundary.

What are the three most common volumes and what do they contain?

1. brainmask.mgz : skull-stripped volume primarily used for troubleshooting

2. wm.mgz : white matter mask also used for troubleshooting

3. aseg.mgz : subcortical segmentation volume

Which surfaces can be viewed in 3D?

The pial, white, and inflated surfaces. The following are examples of overlays: sulcal and curvature maps, thickness maps, and cortical parcellation.

Which surfaces are not intended to be accurate? Why doesn’t this matter?

Areas around the hippocampus and amygdala, and around the midline cut. This doesn't matter because these are subcortical structures, they do not need to be defined by surfaces.

What is the command for opening Freeview?

Freeview -v /path/to/mri/dir -f /path/to/surf/dir

Using the “--help” flag as a resource, how might you open volume brainmask.mgz at coordinates 175, 105, 145?

freeview -v brainmask.mgz --slice 175 105 145