1. PETsurfer Kinetic Modeling Tutorial Data Description

The dynamic PET data were completely synthesized based on on average ROI time activity curves (TACs) from a study using [11C]SB207145 which targets the serotonin 5HT4 receptor (see Beliveau, et all, 2016). These ROI TACs where then applied to the anatomical MRIs of subjects not in the PET study to create PET-like dynamic images. The anatomical images are 18 real subjects distributed as part of the FSFAST fMRI tutorial. The anatomical images were gradient unwarped prior to analyzing in recon-all. The data are suitable for analyzing using the MRTM1 and MRTM2 models. The data were synthesized with both tissue fraction effects (TFEs) and partial volume effects (PVEs). The PVE is an isotropic 6mm Gaussian kernel. The data were simulated with slight differences in subjects according to two (arbitrary) groups so that there will be a group effect in the bindind potentials.

2. Getting the Data (not necessary for the Boston FreeSurfer Course)

Change directory into the project folder. There you will see 18 folders called s01, s02, etc. Change directory into sb01. You will see several files:

tac.vol.nii.gz -- this is a multi frame volume holding the