// Topup - FMRIB's Tool for correction of susceptibility induced distortions // // topup.cpp // // Jesper Andersson, FMRIB Image Analysis Group // // Copyright (C) 2012 University of Oxford /* Part of FSL - FMRIB's Software Library http://www.fmrib.ox.ac.uk/fsl fsl@fmrib.ox.ac.uk Developed at FMRIB (Oxford Centre for Functional Magnetic Resonance Imaging of the Brain), Department of Clinical Neurology, Oxford University, Oxford, UK LICENCE FMRIB Software Library, Release 5.0 (c) 2012, The University of Oxford (the "Software") The Software remains the property of the University of Oxford ("the University"). The Software is distributed "AS IS" under this Licence solely for non-commercial use in the hope that it will be useful, but in order that the University as a charitable foundation protects its assets for the benefit of its educational and research purposes, the University makes clear that no condition is made or to be implied, nor is any warranty given or to be implied, as to the accuracy of the Software, or that it will be suitable for any particular purpose or for use under any specific conditions. Furthermore, the University disclaims all responsibility for the use which is made of the Software. It further disclaims any liability for the outcomes arising from using the Software. The Licensee agrees to indemnify the University and hold the University harmless from and against any and all claims, damages and liabilities asserted by third parties (including claims for negligence) which arise directly or indirectly from the use of the Software or the sale of any products based on the Software. No part of the Software may be reproduced, modified, transmitted or transferred in any form or by any means, electronic or mechanical, without the express permission of the University. The permission of the University is not required if the said reproduction, modification, transmission or transference is done without financial return, the conditions of this Licence are imposed upon the receiver of the product, and all original and amended source code is included in any transmitted product. You may be held legally responsible for any copyright infringement that is caused or encouraged by your failure to abide by these terms and conditions. You are not permitted under this Licence to use this Software commercially. Use for which any financial return is received shall be defined as commercial use, and includes (1) integration of all or part of the source code or the Software into a product for sale or license by or on behalf of Licensee to third parties or (2) use of the Software or any derivative of it for research with the final aim of developing software products for sale or license to a third party or (3) use of the Software or any derivative of it for research with the final aim of developing non-software products for sale or license to a third party, or (4) use of the Software to provide any service to an external organisation for which payment is received. If you are interested in using the Software commercially, please contact Isis Innovation Limited ("Isis"), the technology transfer company of the University, to negotiate a licence. Contact details are: innovation@isis.ox.ac.uk quoting reference DE/9564. */ #include #include #include #include #include #include #include #include "newmat.h" #include "newmatio.h" #ifndef EXPOSE_TREACHEROUS #define EXPOSE_TREACHEROUS // To allow us to use .set_sform etc #endif #include "newimage/newimageall.h" #include "miscmaths/miscmaths.h" #include "miscmaths/nonlin.h" #include "warpfns/warpfns.h" #include "basisfield/basisfield.h" #include "basisfield/splinefield.h" #include "basisfield/dctfield.h" #include "topup_costfunctions.h" #include "topupfns.h" using namespace std; using namespace NEWMAT; using namespace NEWIMAGE; using namespace BASISFIELD; using namespace TOPUP; int main(int argc, char *argv[]) { // Read command line input boost::shared_ptr clp; try { clp = parse_topup_command_line(argc,argv); } catch (const std::exception& error) { cerr << "Topup: Error occured when parsing the command line" << endl; cerr << "Exception thrown with message: " << error.what() << endl; exit(EXIT_FAILURE); } // Read input images NEWIMAGE::volume4D in; try { read_volume4D(in,clp->ImaFname()); } catch (const std::exception& error) { cerr << "Error occurred when reading --imain file " << clp->ImaFname() << endl; cerr << "Exception thrown with message: " << error.what() << endl; exit(EXIT_FAILURE); } // Prepare for running // SCale images to obtain a consistent weighting against regularisation, // and possibly between scans if the scale has not been preserved. std::vector means(in.tsize()); double gmean = 0.0; for (int i=0; iIndividualScaling()) { for (int i=0; i cf; boost::shared_ptr nlpar; try { // Create cost-function object and // set properties for first level cf = boost::shared_ptr(new TopupCF(in,clp->PhaseEncodeVectors(),clp->ReadoutTimes(),clp->WarpRes(1),clp->SplineOrder())); cf->SetTracePrint(clp->Trace()); cf->SetVerbose(clp->Verbose()); cf->SetDebug(clp->DebugLevel()); cf->SetLevel(1); cf->SetRegridding(clp->Regridding(in)); cf->SubSample(clp->SubSampling(1)); cf->Smooth(clp->FWHM(1)); cf->SetMovementsFixed(!clp->EstimateMovements(1)); cf->SetRegularisation(clp->Lambda(1),clp->RegularisationModel()); cf->SetSSQLambda(clp->SSQLambda()); cf->SetHessianPrecision(clp->HessianPrecision()); cf->SetInterpolationModel(clp->InterpolationModel()); // Create non-linear parameters object ColumnVector spar(cf->NPar()); spar = 0; nlpar = boost::shared_ptr(new NonlinParam(cf->NPar(),clp->OptimisationMethod(1),spar)); if (nlpar->Method() == MISCMATHS::NL_LM) { nlpar->SetEquationSolverMaxIter(500); nlpar->SetEquationSolverTol(1.0e-3); } nlpar->SetMaxIter(clp->MaxIter(1)); } catch (const std::exception& error) { cerr << "Error occurred when preparing to run topup" << endl; cerr << "Exception thrown with message: " << error.what() << endl; exit(EXIT_FAILURE); } // Run minimisation at first level try { nonlin(*nlpar,*cf); } catch (const std::exception& error) { cerr << "Error occurred when running first level of topup" << endl; cerr << "Exception thrown with message: " << error.what() << endl; exit(EXIT_FAILURE); } // Run remaining levels to refine solution. unsigned int l=2; try { for ( ; l<=clp->NoOfLevels(); l++) { if (clp->Verbose()) cout << "***Going to next resolution level***" << endl; // Change settings for cost-function object cf->SetLevel(l); cf->Smooth(clp->FWHM(l)); cf->SubSample(clp->SubSampling(l)); cf->SetWarpResolution(clp->WarpRes(l)); cf->SetMovementsFixed(!clp->EstimateMovements(l)); cf->SetRegularisation(clp->Lambda(l),clp->RegularisationModel()); // Make a new nonlinear object nlpar = boost::shared_ptr(new NonlinParam(cf->NPar(),clp->OptimisationMethod(l),cf->Par())); if (nlpar->Method() == MISCMATHS::NL_LM) { nlpar->SetEquationSolverMaxIter(500); nlpar->SetEquationSolverTol(1.0e-3); } nlpar->SetMaxIter(clp->MaxIter(l)); try { nonlin(*nlpar,*cf); } catch (const std::exception& error) { cerr << "Error occurred when running level " << l << " of topup" << endl; cerr << "Exception thrown with message: " << error.what() << endl; exit(EXIT_FAILURE); } } } catch (const std::exception& error) { cerr << "Error occurred when preparing to run level " << l << " of topup" << endl; cerr << "Exception thrown with message: " << error.what() << endl; exit(EXIT_FAILURE); } // Save Everything we have been asked so save try { if (clp->SubSampling(clp->NoOfLevels()) > 1) { cf->SubSample(1); } cf->WriteCoefficients(clp->CoefFname()); cf->WriteMovementParameters(clp->MovParFname()); if (clp->FieldFname().size()) cf->WriteField(clp->FieldFname()); if (clp->ImaOutFname().size()) { cf->Smooth(0.0); cf->SubSample(1); cf->WriteUnwarped(clp->ImaOutFname()); } } catch(const std::exception& error) { cerr << "Error occured while writing output from topup" << endl; cerr << "Exception thrown with message: " << error.what() << endl; exit(EXIT_FAILURE); } exit(EXIT_SUCCESS); }